HYPERTROPIC SCARS & KELOID
A hypertrophic scar is a cutaneous condition characterized by deposits of excessive amounts of collagen which gives rise to a raised scar, but not to the degree observed with keloids. Like Keloids, they form most often at the sites of pimples, body piercings, cuts and burns. They often contain nerves and blood vessels. They generally develop after thermal or traumatic injury that involves the deep layers of the dermis and express high levels of TGF-β.
When a normal wound heals, the body produces new collagen fibers at a rate which balances the breakdown of old collagen.
SIGNS AND SYMPTOMS
Keloids expand in claw-like growths over normal skin.They have the capability to hurt with a needle-like pain or to itch without warning, although the degree of sensation varies from person to person.
Hypertrophic scars are red and thick and may be itchy or painful. They do not extend beyond the boundary of the original wound, but may continue to thicken for up to six months.
The cause is currently unknown but there is speculation that fibroblasts, MMP-2 (Matrix Metalloproteinase-2), and/or TIMP (Tissue Inhibitors of Metalloproteinases) could have some relation to the cause.